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A  Technique for Quantitatively Measuring Gas Uptake in the Lung and its Distribution to the Kidneys Using Hyperpolarized Xenon-129 MR Imaging

Author:Hooman Hamedani  Stephen Kadlecek  Kai Ruppert  Yi Xin  Mehrdad Pourfathi  Sarmad Siddiqui  Faraz Amzajerdian  Luis Loza  Harrilla Profka  Ryan Baron  Tahmina Achekzai  Shampa Chatterjee  Maurizio Cereda  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:08:00  

Session:Thoracic MRI: Lung & Mediastinum  

Program Number:1082  

Presentation Time:09:00  

Room Number:W05/06  

Computer Number:

Assessing the Impact of Acid Aspiration with Hyperpolarized Xenon-129 Dissolved-Phase MRI

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Maurizio Cereda  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:17:15  

Session:Hyperpolarised Compound Imaging  

Program Number:4479  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 90  

A Comparison of Hyperpolarized Helium-3 and Xenon-129 MR Fractional Ventilation Imaging

Author:Hooman Hamedani  Kai Ruppert  Yi Xin  Stephen Kadlecek  Faraz Amzajerdian  Ryan Baron  Ian Duncan  Luis Loza  Mehrdad Pourfathi  Sarmad Siddiqui  Harrilla Profka  Mary Spencer  Tahmina Achekzai  Maurizio Cereda  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Lung MRI  

Program Number:4354  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 84  

Feasibility of Imaging Lung Cancer Using Hyperpolarized MRI Technology

High-Resolution Cardiopulmonary Imaging in Free-Breathing Mice using Hyperpolarized Xenon-129

Author:Luis Loza  Mehrdad Pourfathi  Stephen Kadlecek  Kai Ruppert  Hooman Hamedani  Sarmad Siddiqui  Faraz Amzajerdian  Yi Xin  Ryan Baron  Mary Spencer  Tahmina Achekzai  Ian Duncan  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:08:15  

Session:MRS Applications  

Program Number:3900  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 109  

Imaging Regional Distribution of Metabolic Activity During Progression of Acute Lung Injury using Hyperpolarized Carbon-13 MRI

Author:Mehrdad Pourfathi  Maurizio Cereda  Shampa Chatterjee  Yi Xin  Stephen Kadlecek  Hooman Hamedani  Ian Duncan  Sarmad Siddiqui  Harrilla Profka  Kai Ruppert  Luis Loza  Faraz Amzajerdian  Ryan Baron  Mary Spencer  Tahmina Achekzai  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:Hyperpolarisation: Applications  

Program Number:3707  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 35  

Integrating Magnetic Resonance Imaging with Live Lung Intravital Microscopy: A Novel Platform to Evaluate the Effect of Radiation on Lung Tumors

Author:Shampa Chatterjee  Luis Loza  Mehrdad Pourfathi  Sarmad Siddiqui  Jian Tao  Harrilla Profka  Ian Duncan  Hooman Hamedani  Kai Ruppert  Diane Lim  Yan Liu  Jose Conejo-Garcia  Mary Spencer  Tahmina Achekzai  Stephen Kadlecek  Rahim Rizi  

Author Institution:Moffitt Cancer Center  University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1551  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Investigating Pulmonary Gas Transport Processes with Hyperpolarized Xenon-129 Dissolved-Phase MRI

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:17:15  

Session:Hyperpolarised Compound Imaging  

Program Number:4480  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 91  

Measuring the Impact of PEEP on Pulmonary Gas Transport Using Hyperpolarized Xenon-129 Dissolved-Phase MRI

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Maurizio Cereda  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2435  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

A Multimodal Imaging Approach to Characterize the Onset of Pulmonary Fibrosis

Author:Sarmad Siddiqui  Mehrdad Pourfathi  Stephen Kadlecek  Yi Xin  Harrilla Profka  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:Hyperpolarisation: Applications  

Program Number:3715  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 43  

Myocardial Infarct Border Zone Metabolism Measured by Hyperpolarized 13C-Pyruvate MRI

Author:James Pilla  Gabor Mizsei  Jerry Zsido II  Norman Butler  Yoshiaki Saito  Gabrielle Pilla  , Keitaro Okamoto  Akito Imai  Christopher Gade  Mehrdad Pourfathi  Kai Ruppert  Stephen Kadlecek  Sarmad Siddiqui  Joseph Gorman III  Robert Gorman  Terence Gade  

Author Institution:University of Pennsylvania  Weill Medical Coll of Cornell NY  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:08:00  

Session:CMR Innovations  

Program Number:1054  

Presentation Time:09:24  

Room Number:S03  

Computer Number:

Observing Pulmonary Gas-Transport Dynamics Using Rapid 1D Hyperpolarized Xenon-129 Dissolved-Phase Measurements

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2434  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

Pulmonary Metabolism and Inflammation During Mechanical Ventilation: A Hyperpolarized Carbon-13 Study

Author:Mehrdad Pourfathi  Shampa Chatterjee  Maurizio Cereda  Yi Xin  Stephen Kadlecek  Hooman Hamedani  Ian Duncan  Sarmad Siddiqui  Harrilla Profka  Kai Ruppert  Luis Loza  Faraz Amzajerdian  Ryan Baron  Mary Spencer  Tahmina Achekzai  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:Hyperpolarisation: Applications  

Program Number:3706  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 34  

Regional Lung Function Quantification by Combining Gas-Phase Saturation with Hyperpolarized Xenon-129 Dissolved-Phase MRI

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2433  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

Revealing Pulmonary Gas Transport Dynamics using a 3D Radial Hyperpolarized Xenon MRI Acquisition with Variable Flip Angles

Author:Faraz Amzajerdian  Kai Ruppert  Hooman Hamedani  Yi Xin  Ian Duncan  Harrilla Profka  Mehrdad Pourfathi  Sarmad Siddiqui  Luis Loza  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2437  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

Structural Determination Using 129Xe NMR Line-shape in Chemical Shift Imaging

Structural Determination Using 129Xe NMR Line-shape in Chemical Shift Imaging

A Study of Lung Function Variability in Chronic Obstructive Pulmonary Disease Using Hybrid Hyperpolarized 3He Imaging

Author:Hooman Hamedani  Ryan Baron  Sarmad Siddiqui  Yi Xin  Mary Spencer  Faraz Amzajerdian  Stephen Kadlecek  Kai Ruppert  Mehrdad Pourfathi  Luis Loza  Ian Duncan  Tahmina Achekzai  Maurizio Cereda  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2443  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

Use of Ab-Initio Molecular Dynamics Simulations to Estimate Hyperpolarized 13C Agent Spin-Lattice Relaxation Times

Author:Joe Wildenberg  Stephen Kadlecek  Rahim Rizi  Terence Gade  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:09:15  

Session:Spectroscopy: NMR & Other  

Program Number:4022  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 112  

Use of dissolved-phase 129Xe imaging to visualize gas uptake and distribution in the free-breathing mouse

Author:Luis Loza  Stephen Kadlecek  Mehrdad Pourfathi  Kai Ruppert  Hooman Hamedani  Ian Duncan  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:09:15  

Session:Non-Proton MRS/MRI: Novel Applications  

Program Number:4004  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 94  

Using a hybrid multibreath hyperpolarized (HP) 129Xe imaging technique for simultaneous assessment of lung function and structure in a two-hit radiation induced lung injury (RILI) model.

Author:Sarmad Siddiqui  Hooman Hamedani  Yi Xin  Luis Loza  Faraz Amzajerdian  Mehrdad Pourfathi  Stephen Kadlecek  Kai Ruppert  Harrilla Profka  Rahim Rizi  Shampa Chatterjee  Ian Duncan  

Author Institution:University of Pennsylvania  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:129Xe & 3He Imaging  

Program Number:2439  

Presentation Time:

Room Number:Exhibition Hall 2433-2443  

Computer Number:

Using Regional Gas-Phase Saturation to Localize Hyperpolarized Xenon-129 Spectroscopy Measurements

Author:Kai Ruppert  Hooman Hamedani  Faraz Amzajerdian  Luis Loza  Yi Xin  Ian Duncan  Harilla Profka  Sarmad Siddiqui  Mehrdad Pourfathi  Stephen Kadlecek  Rahim Rizi  

Author Institution:University of Pennsylvania  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:17:15  

Session:Hyperpolarised Compound Imaging  

Program Number:4481  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 92